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Belkyra A Non-Surgical Approach to Double Chin Reduction

A Health Canada approved injectable treatment designed to reduce submental fat, improve chin definition, and enhance the profile without surgery, without anaesthesia, and without permanent downtime.
At DermEsthetics, every Belkyra treatment begins with a thorough clinical assessment of the submental area to confirm that the treatment is appropriate for your anatomy and your goals.
The Science of Beauty

What Is Belkyra?

Belkyra® is an injectable prescription treatment approved by Health Canada specifically for the reduction of submental fullness the accumulation of fat beneath the chin that creates the appearance of a double chin. It has been available in Canada since 2016.
Belkyra contains deoxycholic acid as its active ingredient, a bile acid that occurs naturally in the body and plays a role in the digestion and absorption of dietary fat. Injected into targeted submental fat tissue, it works at the cellular level to permanently disrupt and destroy fat cells in that area, which the body then gradually clears.
Belkyra is not a weight loss treatment. It is specifically designed to treat localized submental fat, appropriate where the double chin appearance is driven primarily by fat accumulation rather than by skin laxity or bone structure.
“The submental area is one of the most emotionally loaded concerns clients bring to us. When someone is bothered by a double chin despite being at a healthy weight, they deserve a genuinely clinical answer not just reassurance.”
The Mechanism

How Belkyra Works

The mechanism behind Belkyra is based on a well-understood property of deoxycholic acid: its ability to disrupt and destroy cell membranes when in direct contact with them.
When a synthetic formulation of this molecule is injected into submental fat tissue, it causes a process called adipocytolysis, the irreversible disruption of the fat cell’s membrane. The fat cell is destroyed, and the resulting cellular debris triggers a mild inflammatory response.
Over the days and weeks following treatment, the body’s immune system sends macrophages to the injection site to gradually clear the treated fat cell material. As this process completes, the volume of fat in the treated area diminishes, and the profile of the chin and jawline progressively improves.
Because the fat cells themselves are destroyed rather than reduced in size, they do not regenerate. However, remaining untreated fat cells can still respond to significant weight gain, which is why maintaining a stable weight supports the longevity of results.

Step 1

Deoxycholic acid injected into submental fat using a precisely mapped grid

Step 2

Fat cell membranes disrupted and destroyed (adipocytolysis)

Step 3

Mild inflammatory response; macrophages begin clearing the debris

Step 4

Fat volume reduces gradually; chin profile improves over weeks

Why Clients Choose Belkyra

Benefits of Belkyra Treatment

Health Canada Approved

Belkyra is the first injectable approved by Health Canada for the permanent reduction of submental fat, with an established record from multiple Phase III trials and nearly a decade of use in Canada.

Permanently Destroys Treated Fat Cells

Once fat cells are destroyed by deoxycholic acid, they do not regenerate, supporting lasting results in clients who maintain a stable weight.

Non-Surgical and Non-Anaesthetic

Belkyra is performed through small injections with a fine needle, with no incisions, no general anaesthesia, and no operating theatre required.

Gradual and Natural-Looking

Results develop progressively as the body clears treated fat cells over weeks, so the improvement looks entirely natural, not like an overnight change. c

Personalized Treatment Planning

The number of sessions, injection mapping, and product volume are tailored to your anatomy, degree of fullness, and goals. There is no standard protocol.

Improved Chin and Jawline Definition

As submental fullness reduces, the chin and jawline become more defined and the overall balance of the lower face often reads as more refined and refreshed.

What Belkyra Treats

Concerns Belkyra Can Help Address

Belkyra is specifically designed for one anatomical area and one type of concern. Understanding whether your concern falls within this scope is the most important first step.

Submental Fullness (Double Chin)

The classic double chin, where excess fat beneath the chin creates a visible fold or rounded appearance, is the primary concern Belkyra is designed to address, when caused by localized fat rather than loose skin or anatomical structure.

Reduced Jawline Definition

Excess submental fat can obscure the transition between the chin and neck, making the jawline appear less defined. Reducing this fat can restore clearer definition to the jaw-to-neck profile.

Persistent Submental Fullness at a Stable Weight

The submental area is often resistant to diet and exercise, as fat distribution is largely determined by genetics. For clients at a stable weight who still carry visible submental fat, Belkyra offers a targeted, non-surgical option.

Pre-Existing Submental Anatomy

Some clients have always had a fuller-appearing chin area due to natural anatomy rather than weight-related change. Belkyra can be appropriate where the fullness is confirmed to be fat tissue at consultation.

Belkyra is not appropriate for submental fullness caused primarily by skin laxity or anatomical bone structure, for concerns in other facial or body areas, or as a replacement for overall weight management. Your specialist will be direct about what Belkyra can and cannot realistically achieve for your specific presentation.
Is This Treatment for You?

Who Is a Good Candidate for Belkyra?

Belkyra is approved and appropriate for adults with moderate to severe submental fullness where the primary contributor is localized fat. Suitability depends on a clinical assessment reviewed at consultation.
Good Candidates Typically
May Not Be Appropriate For
What to Expect

What Happens During Your Belkyra Appointment

01
Consultation and Clinical Assessment
Your specialist assesses the fat distribution, skin quality, and anatomy in detail, and discusses goals, medical history, recovery, session estimate, and realistic timeline.
02
Preparing the Treatment Area
The area is cleansed. Topical numbing may be applied for 20 to 30 minutes. A grid template marks injection points at regular intervals to ensure even coverage.
03
The Treatment
Deoxycholic acid is injected at each marked point. Treatment typically takes 15 to 20 minutes, with brief stinging or burning sensations at each point.
04
Immediately After
You will likely notice redness, swelling, tenderness, and warmth within hours. This is a normal, expected response reflecting the inflammatory process.
05
Follow-Up and Planning
Your specialist confirms post-treatment care and the timing for your next session, spaced a minimum of four weeks apart.
Treatment Planning

How Many Sessions Will You Need?

Belkyra is not a single-session treatment for most clients. The number of sessions depends on the volume of submental fat present and the individual body’s response to treatment.
In clinical practice, most clients with moderate submental fullness achieve satisfying results in two to four sessions. Your specialist will discuss a realistic session estimate for your anatomy at consultation.

Session Spacing

Minimum four weeks, typically four to six weeks between sessions.

Maximum Sessions

Six sessions per Health Canada protocol.

Typical Course

Two to four sessions for most clients with moderate submental fullness.

Final Result Timeline

Visible at four to six weeks after the last session, once fully cleared.

Preparation and Care

Before and After Your Belkyra Treatment

Before Your Appointment
After Your Treatment
Realistic Expectations

Results and Timeline

When Will I See Results?

Visible improvement can be seen as early as four weeks after a session. Results continue to improve across the full course, with the most settled improvement visible four to six weeks after the final session.

Do Fat Cells Come Back?

The fat cells destroyed by Belkyra do not regenerate; this destruction is biologically permanent. Remaining fat cells can still respond to significant weight gain, so a stable weight supports the best long-term results.

Will Swelling Make Me Look Worse First?

Yes, initially, and we prepare every client for this. Swelling is significant, particularly after the first session, and the area will appear larger before it appears smaller. Plan treatment around your schedule accordingly.

Safety and Considerations

Safety, Side Effects, and What to Expect During Recovery

Belkyra has been approved by Health Canada since 2016 with an established safety and clinical efficacy record. When administered with correct grid-based technique, it is well-characterized with predictable, manageable side effects.
Expected Effects
Less Common Effects

When to Contact the Clinic

Contact DermEsthetics if you experience severe or unexpected pain, signs of skin breakdown, significant facial asymmetry affecting your smile, or any other concerning symptoms after treatment.

Contraindications

The marginal mandibular branch of the facial nerve passes near the submental treatment area. Careful grid-based injection technique minimizes this risk. If affected, the smile asymmetry is typically temporary and resolves as the treatment effect clears over weeks.
Understanding Your Options

Belkyra vs Surgical Liposuction What Is the Difference?

There is no universal answer about which is better. It depends on the degree of submental fullness, tolerance for surgery and its risks, the timeline available, and what outcome is realistic for the individual anatomy. If we assess that surgical consultation would serve a client better, we will say so.
Belkyra
Surgical Liposuction
The DermEsthetics Difference

Why Choose DermEsthetics for Your Belkyra Treatment

Belkyra treatment requires precision injection technique and a thorough understanding of the submental anatomy, including the marginal mandibular nerve risk minimized by correct technique.
At DermEsthetics, every Belkyra treatment is delivered by a trained, credentialed member of our medical aesthetics team, working to protocols developed under the oversight of our founder and clinical director, Sadia Tarar, Aesthetic Expert an International Medical Graduate with over 25 years of combined medical and aesthetics experience.

Thorough Pre-Treatment Assessment

We assess the submental anatomy, skin quality, and driving cause of your double chin at consultation before recommending any treatment. If Belkyra is not the most appropriate approach, we will tell you.

Honest Recovery Preparation

We explain the post-treatment swelling, firmness, and numbness in detail before you begin, not afterward. Clients who are prepared have a significantly better experience.

Session Planning That Fits Your Life

We discuss realistic session numbers, spacing, and the overall timeline before you commit to any treatment. We will not rush the planning of a multi-session treatment.

Questions Answered

Frequently Asked Questions

What is Belkyra and what does it contain?
Belkyra is an injectable prescription treatment approved by Health Canada for reduction of submental fat (double chin). It contains deoxycholic acid, a naturally occurring bile acid that permanently destroys fat cells when injected into submental tissue. Belkyra is the Canadian brand name for the same active ingredient marketed as Kybella in the United States.
Most clients need two to four sessions for moderate submental fullness. Some see satisfactory results after one to two sessions. The maximum approved number is six, spaced at least four weeks apart. Your specialist will give a realistic estimate at consultation.
Results do not appear immediately. Visible improvement can be seen as early as four weeks after a session. The final, most significant improvement is typically visible four to six weeks after the last session.
Yes, significantly. The first session typically produces the most noticeable swelling. The area may appear larger before it appears smaller. Swelling typically peaks in 48 to 72 hours and reduces over 1 to 2 weeks.
The most significant swelling typically resolves within one to two weeks. Some residual swelling, firmness, or numbness can persist for several weeks, and numbness in particular can last weeks to months for some clients.
The fat cells destroyed by Belkyra do not regenerate, a biologically permanent process. However, if significant weight is gained, remaining fat cells in the area can enlarge. Maintaining a stable weight supports the best long-term results.
Most clients describe the injections as brief stinging or burning sensations. Topical numbing cream is applied before treatment. Post-treatment, the area will be tender and swollen for several days, generally manageable with acetaminophen.
Belkyra has been approved by Health Canada since 2016 with an established safety record from multiple Phase III trials and years of clinical use. When performed by a trained specialist, it is well-characterized with predictable, manageable side effects.
The marginal mandibular branch of the facial nerve runs near the treatment area. If affected, it can temporarily cause smile asymmetry. This is uncommon and minimized by precise grid-based technique, and typically resolves as the effect diminishes.
Phase III trials showed skin laxity was not worsened in most patients, with some evidence of collagen stimulation. Skin quality is assessed at consultation. If skin laxity is the primary driver rather than fat, other treatments may be more appropriate.
Your specialist will advise at consultation. Some clients combine submental fat reduction with jawline or chin filler for a comprehensive lower face improvement. Timing and sequencing are determined individually.
Avoid alcohol, aspirin, and blood-thinning supplements for 5 to 7 days before treatment. Arrive with clean skin. Do not schedule treatment within weeks of a major event where visible swelling would be a concern.
Belkyra is Health Canada approved only for submental fat. Its use in other areas is off-label and outside the scope of our Belkyra service at DermEsthetics.
Pricing is discussed at consultation and depends on the volume of product required and the number of sessions planned, provided transparently before any treatment is booked.
You can book a consultation through the button on this page, by calling +1 905-271-8164, or by reaching out on WhatsApp at +1 416-456-0883 or via Instagram.

Start With a Conversation About Your Chin Profile

If submental fullness has been a source of self-consciousness, our team will assess your anatomy honestly and build a realistic treatment plan around what can actually be achieved.